Epstein-Barr virus co-opts ADAR1 to evade PKR activation of the integrated stress response in nasopharyngeal carcinoma
Shane A. Wiebe, Ming Guan Ng, Adlina Roslan, Sok Ching Cheong, Annie Wai Yeeng Chai
This study shows EBV uses ADAR1 to prevent PKR activation of the ISR, enabling lytic reactivation and evasion of host immune responses in NPC.
bioRxiv · Oct 9, 2026 · PreprintCancer Biology