Author

Mingshen Chen

Stony Brook University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

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Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Research Focus:polygenic risk· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

David K. ParkiD· 1 shared Hyoung Seop KimiD· 1 shared Jiook ChaiD· 1 shared Jong Hun KimiD· 1 shared Rebekah K. LovingiD· 1 shared Seungsoo KimiD· 1 shared Shinjae YooiD· 1 shared Yoonjung Yoonie JooiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperGenomics

David K. ParkORCID

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1 paper

Recent·Most cited

Overestimated Polygenic Prediction due to Overlapping Subjects in Genetic Datasets

David K. Park, Mingshen Chen, Seungsoo Kim, Yoonjung Yoonie Joo, Rebekah K. Loving, Hyoung Seop Kim, Jiook Cha, Shinjae Yoo, Jong Hun Kim

This paper shows that polygenic risk scores (PRS) overestimate predictive accuracy when datasets have overlapping subjects, using Alzheimer's disease and other traits as examples.

bioRxiv · Jan 19, 2022 · PreprintGenomics