Old mice have a functionally distinct contractile reserve from obese mice
Sarah L. Sturgill, Mohammed Aidja, Benjamin Hu, Mark T. Ziolo
This study uses speckle tracking echocardiography to compare contractile reserve in old and obese mice, finding distinct functional phenotypes in their cardiac responses to preload and sympathetic stimulation.
bioRxiv · May 13, 2025 · PreprintPhysiology