PepCABO: Latent-space Bayesian optimization for peptide-MHC binding using contrastive alignment
Mohsen Ghane, Dani Korpela, Alexandru Dumitrescu, H Lähdesmäki
PepCABO improves peptide-MHC binding optimization using contrastive alignment and Bayesian optimization in a latent space, outperforming baselines across multiple alleles.
bioRxiv · Mar 16, 2026 · PreprintBioinformatics