Comprehensive analysis of nonsense-mediated mRNA decay targets and activity in cardiomyocytes
Mohsen Naghizadeh, Ahmed Alameldeen, Rebecca Kistler, Doris Lindner, Verena Kamuf‐Schenk, Mirko Völkers, Johanna Schott, Timon Seeger, Georg Stoecklin
The paper identifies NMD targets and activity in cardiomyocytes using SMG1 inhibition and RNA sequencing, showing conserved targets and reduced efficiency with UPF1/UPF2 knockdown.
bioRxiv · Jan 12, 2026 · PreprintMolecular Biology