Author

Moises Cosme

Yale University

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Dereck Dokyi Amakye· 1 shared Elijah PaintsiliD· 1 shared Lei ZhouiD· 1 shared Min Li· 1 shared Velma Eduafo· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperPharmacology & Toxicology

Dereck Dokyi Amakye

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1 paper

Recent·Most cited

Activation of NLRP3 inflammasome/pyroptosis by protease inhibitor atazanavir at high concentrations is mediated through mitochondrial dysfunction

Lei Zhou, Moises Cosme, Min Li, Velma Eduafo, Dereck Dokyi Amakye, Elijah Paintsil

This study shows high concentrations of atazanavir induce mitochondrial dysfunction and NLRP3 inflammasome/pyroptosis in T cells, leading to apoptosis.

bioRxiv · Jun 18, 2024 · PreprintPharmacology & Toxicology