Author

Lei Zhou

Yale UniversityORCID 0000-0001-6293-3365Unclaimed ORCID profile · follow to get notified of new preprints

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Lei Zhou4 papers · National University of Singapore

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Dereck Dokyi Amakye· 1 shared Elijah PaintsiliD· 1 shared Min Li· 1 shared Moises Cosme· 1 shared Velma Eduafo· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperPharmacology & Toxicology

Dereck Dokyi Amakye

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 18, 2024

Activation of NLRP3 inflammasome/pyroptosis by protease inhibitor atazanavir at high concentrations is mediated through mitochondrial dysfunction

Lei Zhou, Moises Cosme, Min Li…·Elijah Paintsil

This study shows high concentrations of atazanavir induce mitochondrial dysfunction and NLRP3 inflammasome/pyroptosis in T cells, leading to apoptosis.

DOI 10.1101/2024.06.18.599585

humanbulk RNA-seq

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