GJB3, a gap junction gene, supports cell growth by mediating cystine uptake and regulating cellular stress pathways in SLC7A11 low adenocarcinomas
Disha Acharya, Annesha Chatterjee, Nikita Bhandari, Payel Roy, Monishka Agrawal, Balkrishna Chaube, Sudhanshu Kumar Shukla
This study identifies GJB3 as a key gene in adenocarcinomas with low SLC7A11, showing it supports cell growth through cystine uptake and stress pathway regulation.
bioRxiv · Dec 3, 2024 · PreprintCancer Biology