Sudhanshu Kumar Shukla

TGFb Regulated Small GTPase RHOV interact with PEAK1 and drive MYC Expression to Promote Cellular Proliferation, Migration and Etoposide resistance

This paper identifies RHOV as a prognostic biomarker in NSCLC, showing it drives proliferation, migration, and etoposide resistance through the RHOV-PEAK1-MYC axis.

MRPL47 Deficiency Drives Mitochondrial Dysfunction via ROS/p38-MAPK/CDKN1A Signaling in Non-Small Cell Lung Cancer

This study identifies MRPL47 as an amplified and overexpressed gene in NSCLC that promotes tumor progression by disrupting mitochondrial function and ROS signaling.

GJB3, a gap junction gene, supports cell growth by mediating cystine uptake and regulating cellular stress pathways in SLC7A11 low adenocarcinomas

This study identifies GJB3 as a key gene in adenocarcinomas with low SLC7A11, showing it supports cell growth through cystine uptake and stress pathway regulation.

Development of Machine Learning Model for Pan-cancer Subgroup Identification using Multi-omics Data

This paper develops a machine learning model to identify novel pan-cancer subgroups using multi-omics data, showing that patients with different tumor types can share similar molecular characteristics.