Exposure to the organochlorine pesticide cis-chlordane induces ALS-like mitochondrial perturbations in stem cell-derived motor neurons
Oliver Clackson, Muhammad Reza Hamid, Adithi Wijesekera, Daniel Kulick, Alison O’Neil
This study shows that cis-chlordane exposure causes mitochondrial dysfunction in motor neurons, resembling ALS features, and suggests its role in ALS pathogenesis.
PLoS ONE · Oct 14, 2025Peer-reviewedNeuroscience