Meta-analysis of genome-wide association studies of doxorubicin-induced arrhythmia identifies MMP16 and KCTD15 as risk loci
Joseph S. Reddy, Milagros Pereyra, Mohammed Tiseer Abbas, Reza Arsanjani, Isaac Prah, Nicholas James Boddicker, James R. Cerhan, Melissa C. Larson, Mwangi Raphael, Thomas Matthew Habermann, Hector R. Villarraga, Robert Alan Vierkant, Anthony C. Luehrs, Hugues Sicotte, Jan B. Egan, , Nadine Norton
This study identifies genetic risk loci for doxorubicin-induced arrhythmia through GWAS meta-analysis and validates their functional relevance in human and zebrafish models.
Circulation Genomic and Precision Medicine · Jul 29, 2026Peer-reviewedGenetic & Genomic Medicine