Author

N. A. Grant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 5 Microbiology· 1

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Approach:experimental assay· 5 Organism:E. coli· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

R. Maddamsetti· 3 shared R. E. Lenski· 2 shared A. Abdel Magid· 1 shared A. J. Ferguson· 1 shared A. M. Lalejini· 1 shared A. Tillman· 1 shared B. A. Sommerfeld· 1 shared C. M. Waters· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersEvolutionary Biology

R. Maddamsetti

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Author profile →

6 papers

Recent·Most cited

Deployment of a Vibrio cholerae ordered transposon mutant library in a quorum-competent genetic background

N. A. Grant, G. Y. Donkor, J. T. Sontz, W. Soto, C. M. Waters

The paper generates a quorum-sensing competent transposon mutant library for Vibrio cholerae by transferring mutants into a wildtype background, revealing density-dependent epistasis and improving genetic context for studying pathogenesis.

bioRxiv · Oct 31, 2023 · PreprintMicrobiology

Adaptive phenotypic plasticity stabilizes evolution in fluctuating environments

A. M. Lalejini, A. J. Ferguson, N. A. Grant, C. Ofria

This study shows that adaptive phenotypic plasticity reduces evolutionary change and stabilizes populations in fluctuating environments by preventing the accumulation of maladaptive alleles.

bioRxiv · May 25, 2021Evolutionary Biology

Changes in Cell Size and Shape During 50,000 Generations of Experimental Evolution with Escherichia coli

N. A. Grant, A. Abdel Magid, J. Franklin, Y. S. Dufour, R. Lenski

This study tracks changes in cell size and shape over 50,000 generations of Escherichia coli evolution, showing increased cell size and fitness, with variation in shape across populations.

bioRxiv · Aug 13, 2020Evolutionary Biology

Maintenance of metabolic plasticity despite relaxed selection in a long-term evolution experiment with Escherichia coli

N. A. Grant, R. Maddamsetti, R. E. Lenski

The paper examines how relaxed selection affects metabolic plasticity in E. coli over 30 years, finding that anaerobic fitness is maintained despite relaxed selection.

bioRxiv · Jun 2, 2020Evolutionary Biology

Discovery of positive and purifying selection in metagenomic time series of hypermutator microbial populations

R. Maddamsetti, N. A. Grant

The paper introduces STIMS, a method to detect positive and purifying selection in metagenomic time series of hypermutator microbial populations, showing its effectiveness in real-time evolution studies.

bioRxiv · May 23, 2020Evolutionary Biology

Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment

Z. D. Blount, R. Maddamsetti, N. A. Grant, S. T. Ahmed, T. Jagdish, B. A. Sommerfeld, A. Tillman, J. P. Moore, J. L. Slonczewski, J. E. Barrick, R. E. Lenski

This study examines the genomic and phenotypic evolution of Escherichia coli in a citrate-only environment, identifying copy-number variations and transposable elements as key factors, while noting persistent physiological mismatches.

bioRxiv · Jan 22, 2020Evolutionary Biology