Author

N. Dokholyan

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

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C. W. Carter· 1 shared G. Weinreb· 1 shared J. Das· 1 shared S. N. Chandrasekaran· 1 shared V. Weinreb· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperBiophysics

C. W. Carter

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1 paper

Recent·Most cited

Thermodynamic impacts of combinatorial mutagenesis on protein conformational stability: precise, high-throughput measurement by Thermofluor

C. W. Carter, V. Weinreb, G. Weinreb, S. N. Chandrasekaran, J. Das, N. Dokholyan

The paper uses Thermofluor to measure the thermodynamic effects of combinatorial mutations on TrpRS stability, showing strong agreement with computational models and CD melting profiles.

bioRxiv · Mar 27, 2019 · PreprintBiophysics