Combinatorial approaches using an AI/ML-driven drug development platform targeting insulin resistance, lipid dysregulation, and inflammation for the amelioration of metabolic syndrome in patients
M. Khotimchenko, M. S. Hixon, N. E. Brunk, D. M. Walden, H. Hou, K. Chakravarty, J. Varshney
The paper proposes a combinatorial drug approach using FDA-approved compounds targeting IL-17a and DPP4 to treat metabolic syndrome, using an AI/ML platform to identify promising drug candidates.
bioRxiv · Sep 1, 2021 · PreprintPharmacology & Toxicology