Author

N. El-Hachem

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

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B. Haibe-Kains· 1 shared P. Smirnov· 1 shared R. Quevedo· 1 shared T. J. Pugh· 1 shared Z. Safikhani· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperCancer Biology

B. Haibe-Kains

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1 paper

Recent·Most cited

Karyotypic divergence confounds cellular phenotypes in large pharmacogenomic studies

R. Quevedo, N. El-Hachem, P. Smirnov, Z. Safikhani, T. J. Pugh, B. Haibe-Kains

This study identifies discordances in genotypic and karyotypic profiles across pharmacogenomic datasets, highlighting the impact of copy-number variants on drug response and the need for verification of cell line profiles.

bioRxiv · Mar 11, 2019 · PreprintCancer Biology