Author

N. L. V. O'Brien

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Evolutionary Biology· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:statistical model· 1

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B. Holland· 1 shared D. Ortiz-Barrientos· 1 shared J. Engelstaedter· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperEvolutionary Biology

B. Holland

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Evolutionary BiologybioRxivOct 26, 2023

The distribution of fitness effects during adaptive walks using a simple genetic network

N. L. V. O'Brien, B. Holland, J. Engelstaedter, D. Ortiz-Barrientos

This study models adaptation using a genetic network and finds that fitness effect distributions differ from theoretical expectations, showing fewer large-effect beneficial mutations and a bimodal distribution in the network model.

DOI 10.1371/journal.pgen.1011289

statistical modelchromatin & epigenetic regulation

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