Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts
P. Kamat, N. Macaluso, C. Min, Y. Li, A. Agrawal, A. Winston, L. Pan, B. Starich, T. Stewert, P.-H. Wu, J. Fan, J. Walston, J. M. Phillip
This study identifies functional senescence subtypes in aging human dermal fibroblasts using single-cell morphology and machine learning, showing subtype-specific responses to senotherapies.
bioRxiv · May 10, 2024Bioengineering