Treatment of human cells with 5-aza-dC induces formation of PARP1-DNA covalent adducts at genomic regions targeted by DNMT1
This study shows that 5-aza-dC treatment causes PARP1 to form covalent DNA adducts at DNMT1-targeted genomic regions, potentially contributing to cell death.
bioRxiv · Aug 4, 2020Biochemistry