Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers
N. N. Louros, M. Ramakers, E. Michiels, K. Konstantoulea, C. Morelli, T. Garcia, S. D'Haeyer, V. Goossens, D. Audenaert, F. Rousseau, J. Schymkowitz
The paper identifies sequence-specific rules governing heterotypic amyloid interactions and shows how they can modify amyloid assembly and contribute to neurodegenerative disease progression.
bioRxiv · Jun 4, 2021Biophysics