Induction of tumor-initiating cells and glioma-initiating cells from fetal neural stem cells through p53 genome editing
This study induces glioma-initiating cells (GICs) from fetal neural stem cells using p53 genome editing and HRasL61 overexpression, showing their tumorigenicity but not invasiveness.
bioRxiv · Feb 24, 2022 · PreprintCell Biology