Direct conversion of human fibroblasts to pancreatic epithelial cells through transient progenitor states is controlled by temporal activation of defined factors
L. Fei, K. Zhang, N. Poddar, S. Hautaniemi, B. Sahu
This study reprograms human fibroblasts to pancreatic exocrine cells using six transcription factors and identifies transient progenitor states as key intermediates in the process.
bioRxiv · Nov 16, 2022 · PreprintCell Biology