Author

L. Fei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:deep learning· 3 Organism:human· 3 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. J. Radtke· 1 shared A. V. Predeus· 1 shared A. Y. Kreins· 1 shared B. Sahu· 1 shared B. Wachter· 1 shared B. Xie· 1 shared C. Suo· 1 shared C. Tudor· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. J. Radtke

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A spatial human thymus cell atlas mapped to a continuous tissue axis

N. Yayon, V. R. Kedlian, L. Boehme, C. Suo, B. Wachter, R. T. Beuschel, O. Amsalem, K. Polanski, S. Koplev, E. Tuck, E. Dann, J. Van Hulle, S. Perera, T. Putteman, A. V. Predeus, , Tag

The paper maps the spatial organization of the human thymus across developmental stages using a multimodal atlas and identifies key cellular and molecular features of T cell development.

bioRxiv · Oct 25, 2023Immunology

Co-engagement of TIGIT+ immune cells to PD-L1+ tumours by a bispecific antibody potentiates T-cell response and tumour control

X. Cui, H. Yu, X. Zhu, J. Xu, X. Wei, S. Chen, Y. Wang, X. Chen, Y. Feng, X. Ren, L. Fei, B. Xie, M. Li, X. Li, H. Jia, , Y. Zhan

This paper shows that a bispecific antibody targeting PD-L1 and TIGIT enhances T-cell response and tumor control compared to using the individual antibodies.

bioRxiv · May 11, 2023 · PreprintImmunology

The Hereditary and Epigenetic Fusion Gene Signatures of Multiple Myeloma

L. Fei, N. Zhuo, D. Zhuo

The paper identifies hereditary and epigenetic fusion genes in multiple myeloma using RNA-Seq data from 727 patients, showing that some fusion genes are hereditary and others are epigenetic.

bioRxiv · Dec 5, 2022 · PreprintCancer Biology

Direct conversion of human fibroblasts to pancreatic epithelial cells through transient progenitor states is controlled by temporal activation of defined factors

L. Fei, K. Zhang, N. Poddar, S. Hautaniemi, B. Sahu

This study reprograms human fibroblasts to pancreatic exocrine cells using six transcription factors and identifies transient progenitor states as key intermediates in the process.

bioRxiv · Nov 16, 2022 · PreprintCell Biology