MicroED structure of a protoglobin reactive carbene intermediate
E. Danelius, N. Porter, J. Unge, F. Arnold, T. Gonen
The paper determines the MicroED structure of an Aeropyrum pernix protoglobin variant, revealing how mutations enhance carbene transfer activity and stabilize a reactive iron-carbenoid intermediate.
bioRxiv · Oct 18, 2022Biochemistry