Identification of the Rigid Core for Aged Liquid Droplets of the TDP-43 Low Complexity Domain
B. D. Fonda, K. M. Jami, N. R. Boulos, D. T. Murray
This study identifies a structured core in aged TDP-43 liquid droplets that resists fibril formation, revealing functional and pathological interactions within the low complexity domain.
bioRxiv · Mar 1, 2021Biophysics