Lamina and Heterochromatin Direct Chromosome Organisation in Senescence and Progeria
M. Chiang, D. Michieletto, C. A. Brackley, N. Rattanavirotkul, H. Mohammed, D. Marenduzzo, T. Chandra
This study uses polymer physics simulations to show that lamina and heterochromatin interactions drive nuclear organization in senescence and progeria through phase transitions.
bioRxiv · Nov 13, 2018Biophysics