The structural basis of the multi-step allosteric activation of Aurora B kinase
D. Segura-Pena, O. Hovet, H. Gogoi, J. M. Dawicki-McKenna, S. M. Hansen Woien, M. Carrer, B. E. Black, M. Cascella, N. Sekulic
This study investigates how phosphorylation in Aurora B and IN-box activates the [Aurora B/IN-box] complex through molecular dynamics and structural analysis.
bioRxiv · Nov 23, 2022Biochemistry