The non-classic psychedelic muscimol suppresses inflammatory signaling and promotes neuroplasticity in schizophrenia-derived human cortical spheroids and astroglia
Ibrahim A. Akkouh, Jordi Requena Osete, Thor Ueland, N. W. Steen, Ole A. Andreassen, Srdjan Djurovic, Attila Szabó
This study shows muscimol, a non-classic psychedelic, reduces inflammation and promotes neuroplasticity in schizophrenia-derived human cortical spheroids and astrocytes by modulating GABAA receptors.
bioRxiv · Apr 12, 2026 · PreprintNeuroscience