Nardilysin regulates Slc2a2 expression through ISLET1 recruitment to an evolutionarily conserved enhancer in pancreatic β-cells
Kiyoto Nishi, Narangerel Ganbaatar, Mikiko Ohno, Shinya Ikeda, Hirotaka Iwasaki, Mend Amar Batbaatar, Enkhjin Gansukh, Eiichiro Nishi
This study identifies NRDC's role in regulating Slc2a2 expression in pancreatic β-cells through direct interaction with an evolutionarily conserved enhancer and ISLET1 recruitment.
bioRxiv · Feb 19, 2026 · PreprintCell Biology