BiophysicsbioRxivPreprint
Computational modelling of specific serotonin reuptake inhibitor inhibition on the TREK-2 channel
Narawit Pratueangsukpong, Tanadet Pipatpolkai
This study uses molecular dynamics to show how fluoxetine and escitalopram inhibit TREK-2 channels through different mechanisms involving the selectivity filter and lipid interactions.
DOI 10.1101/2024.05.01.592054