Author

Natalie Leroudier

Centre National de la Recherche Scientifique

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Neuroscience· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Davide MeiiD· 1 shared Marialuisa Ricci· 1 shared Massimo MantegazzaiD· 1 shared Renzo GuerriniiD· 1 shared Sandra Difhallah· 1 shared Sandrine CestèleiD· 1 shared Simona BalestriniiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Davide MeiORCID

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1 paper

Recent·Most cited

Non-syndromic autism-associated SCN2A variants selectively exert dominant-negative effects on NaV1.2 channels.

Sandrine Cestèle, Renzo Guerrini, Sandra Difhallah, Davide Mei, Natalie Leroudier, Marialuisa Ricci, Simona Balestrini, Massimo Mantegazza

The paper investigates the functional impact of SCN2A variants associated with non-syndromic autism, finding that only non-syndromic ASD variants cause dominant-negative effects on Nav1.2 channels.

bioRxiv · Feb 25, 2026 · PreprintNeuroscience