Reversible fixation of microbial cells for targeted genomics
Joan Pamela Engelberts, Kenneth Wasmund, Marc Mußmann, Nataliia Solntseva, Fátima C. Pereira, Christian Rinke, Apoorva Prabhu, James G. Volmer, Buck T. Hanson, Bela Hausmann, Jay Osvatic, Gene W. Tyson, Simon Jon McIlroy, Alexander Loy
This paper introduces DSP as a reversible fixative for microbial cells that enables fluorescence imaging and DNA extraction, improving targeted microbial genomics.
bioRxiv · Oct 22, 2026 · PreprintMicrobiology