A widespread hydrogenase drives fermentative growth of gut bacteria in healthy people
Caitlin Welsh, Princess R. Cabotaje, Vanessa R. Marcelino, Thomas D. Watts, Duncan J. Kountz, Marion Jespersen, Jodee A. Gould, Nhu Quynh Doan, James P. Lingford, Thilini Koralegedara, Jessica Solari, Gemma L. D’Adamo, Ping Jie Huang, Natasha Bong, Emily L. Gulliver, , Chris Greening
This study identifies the group B [FeFe]-hydrogenase as the primary enzyme driving fermentative H2 production in the human gut, linking it to gut health and disease.
Nature Microbiology · Oct 23, 2025Peer-reviewedMicrobiology