The RNA helicase DDX3 induces neural crest by promoting AKT activity
Mark Perfetto, Xiaolu Xu, Congyu Lu, Yu Shi, Natasha Yousaf, Jiejing Li, Yvette Y. Yien, Shuo Wei
This study shows that DDX3 promotes neural crest development by enhancing AKT activity, which is critical for craniofacial morphogenesis and linked to intellectual disability in humans.
Development · Jan 1, 2020Peer-reviewedDevelopmental Biology