An agent-based 3D model of non-genetic adaptation in cancer tissues under electrical, mechanical, and hypoxic stress
João Ferreira Gil, Nathalia Pinheiro, Saverio Gentile, Gil Gonçalves, Rosalia Moreddu
This paper develops an agent-based 3D tumor model to study non-genetic adaptation under electrical, mechanical, and hypoxic stress, showing how these factors shape phenotypic heterogeneity and adaptive memory.
bioRxiv · Sep 2, 2026 · PreprintBiophysics