Targeting GSK-beta with Peptide Inhibitors: A Rational Computational Strategy for Alzheimer's Disease Intervention
Sara Zareei, Saeed Pourmand, Negin Rahimi, Shokoufeh Massahi
This study identifies a kappa casein-derived peptide, MP31, as a potential inhibitor of GSK-3β, showing stable binding and structural stabilization of the enzyme, suggesting therapeutic potential for Alzheimer's disease.
bioRxiv · Dec 30, 2024 · PreprintBiochemistry