Author

Neil Wilkie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dan Leggate· 1 shared Martine van den Heever· 1 shared Nina TruteriD· 1 shared Raminderpal Singh· 1 shared Shade HorniD· 1 shared Shaw KjiD· 1 shared Wikus BerghiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Dan Leggate

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1 paper

Recent·Most cited

Signaling pathway evaluation of leading ATRi, PARPi and CDK7i cancer compounds targeting the DNA Damage Response using Causal Inference

Nina Truter, Wikus Bergh, Martine van den Heever, Shade Horn, Shaw Kj, Dan Leggate, Neil Wilkie, Raminderpal Singh

This paper uses causal inference to evaluate resistance mechanisms of DDR inhibitors in cancer, identifying pathway-specific resistance drivers and potential combination therapies.

bioRxiv · Feb 15, 2024 · PreprintBioinformatics