Author

Nicolas Lynn

Tel Aviv University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:CRISPR screen· 1 Organism:human· 1 Research Focus:software / tool· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Tamir TulleriD· 2 shared Shai Cohen· 1 shared Shaked BergmaniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersSynthetic Biology

Tamir TullerORCID

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2 papers

Recent·Most cited

A tool for CRISPR-Cas9 gRNA evaluation based on computational models of gene expression

Shai Cohen, Shaked Bergman, Nicolas Lynn, Tamir Tuller

EXPosition is a computational tool for CRISPR gRNA design that optimizes gene expression effects using deep learning models for transcription, splicing, and translation initiation.

bioRxiv · Jun 8, 2024 · PreprintSynthetic Biology

Detecting and understanding meaningful cancerous mutations based on computational models of mRNA splicing

Nicolas Lynn, Tamir Tuller

This paper introduces Oncosplice, a tool that identifies deleterious cancer mutations by analyzing mRNA splicing, finding 8K significant variants with 94% positive predictive value.

npj Systems Biology and Applications · Mar 7, 2024Peer-reviewedGenetic & Genomic Medicine