Author

Shai Cohen

Tel Aviv University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1 Organism:plant (other)· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Shaked BergmaniD· 2 shared Tamir TulleriD· 2 shared Adi Yahalom· 1 shared Alina Wiener· 1 shared Amir SagiiD· 1 shared Anat Lavi-Itzkovitz· 1 shared Anat Maoz· 1 shared Anna RiceiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Shaked BergmanORCID

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2 papers

Recent·Most cited

Context-dependent determinants of CRISPR-Cas9 editing efficiency revealed through cross-species endogenous editing analysis

Shai Cohen, Shaked Bergman, Adi Yahalom, Alina Wiener, Anat Lavi-Itzkovitz, Anat Maoz, Anna Rice, Dan Dominissini, Dana Furest, David Simanovich Zini, Dongqi Li, Dov Gertz, Ehud Landau, Ester Yeshayahou, Eyal Emmanuel, , Tamir Tuller

The paper identifies context-dependent factors affecting CRISPR-Cas9 editing efficiency across species using endogenous editing data and shows that repair outcomes are conserved.

bioRxiv · Mar 18, 2026 · PreprintSynthetic Biology

A tool for CRISPR-Cas9 gRNA evaluation based on computational models of gene expression

Shai Cohen, Shaked Bergman, Nicolas Lynn, Tamir Tuller

EXPosition is a computational tool for CRISPR gRNA design that optimizes gene expression effects using deep learning models for transcription, splicing, and translation initiation.

bioRxiv · Jun 8, 2024 · PreprintSynthetic Biology