Author

Nicole M. Fama

West Virginia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:phylogenetics / evolution· 1 Organism:plant (other)· 1 Approach:simulation· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Brandon T. SinniD· 2 shared Craig F. BarrettiD· 2 shared Gerardo A. SalazariD· 1 shared John V. FreudensteiniD· 1 shared Mathilda V. SanteeiD· 1 shared Sandra J. Simon· 1 shared Sandra SimoniD· 1 shared Stephen Paul DiFazioiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

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2 shared papersEvolutionary Biology

Brandon T. SinnORCID

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2 papers

Recent·Most cited

Unexpected excess heterozygosity in a threatened, mycoheterotrophic, self-pollinating orchid

Craig F. Barrett, Nicole M. Fama, John V. Freudenstein, Gerardo A. Salazar, Sandra Simon, Brandon T. Sinn

The paper investigates excess heterozygosity in the self-pollinating orchid Corallorhiza bentleyi, finding overdominance likely explains the phenomenon despite selfing and small population size.

bioRxiv · Oct 9, 2026 · PreprintEvolutionary Biology

ISSRseq: an extensible method for reduced representation sequencing

Brandon T. Sinn, Sandra J. Simon, Mathilda V. Santee, Stephen Paul DiFazio, Nicole M. Fama, Craig F. Barrett

ISSRseq is a PCR-based method for reduced representation sequencing that generates SNP data with simple wet-lab skills and bioinformatics tools, demonstrating high repeatability and utility for non-model organisms.

Methods in Ecology and Evolution · Dec 10, 2021Peer-reviewedGenomics