Mutation rates and adaptive variation among the clinically dominant clusters of Mycobacterium abscessus
Nicoletta Commins, Mark R. Sullivan, Kerry McGowen, Evan M Koch, Eric J. Rubin, Maha Reda Farhat
The paper shows that phylogenetic clustering in Mycobacterium abscessus is linked to reduced mutation rates and DNA repair gene variation, suggesting adaptation rather than transmission as the cause.
Proceedings of the National Academy of Sciences · May 22, 2023Peer-reviewedGenomics