Deep Learning with Evolutionary Scale Modeling to discover Antibiotic-Resistance Drug against Klebsiella Pneumoniae
Linxiao Jin, Zhihao Lei, Peng Lin, Cong Ma, Wen Zhang, Jiali Zhou, Sijun Meng, Zhenghua Jiang, Yemei Bu, Yan Xu, Nijun Wei, Tsehao Hsu, Glen Qin, Hesong Qiu
This study uses deep learning to identify potential antibiotic-resistant drug candidates against Klebsiella pneumoniae by analyzing molecular similarities between drugs and bacterial strains.
bioRxiv · Nov 9, 2024 · PreprintBioinformatics