L2 loop engineering enhances the enzymatic activity and synergism property of the AA16 family Lytic polysaccharide monooxygenase enzyme from Aspergillus fumigatus.
Musaddique Hossain, Shalini Das, Soumyadeep Ray, Nilanjana Bose, Bishwajit Kundu, Sudit Sekhar Mukhopadhyay
This study replaces the L2 loop in AfLPMO16 with loops from other LPMOs, finding that the CsLPMO9 loop enhances enzymatic activity and synergism.
bioRxiv · Aug 27, 2025 · PreprintBiochemistry