Robust Methods For Quantifying Neuronal Morphology And Molecular Signaling Reveal That Psychedelics Do Not Induce Neuroplasticity
Umed Boltaev, Hyun W. Park, Keaon R. Brown, Maya Delgado, Jorryn Wu, Brianna N. Diaz-Pacheco, Maria Botero-Pinzon, Keer He, Erin Ahern, Nina Goldshmid, Eleanor H. Simpson, Dalibor Sameš
This study challenges the idea that psychedelics induce neuroplasticity by showing they do not modulate TrkB or BDNF-TrkB signaling or cause dendritic growth in neuronal cultures.
bioRxiv · Mar 4, 2024 · PreprintNeuroscience