Evolution of Environmentally-Enforced, Repeat Protein Topology in the Outer Membrane
Meghan Whitney Franklin, Sergey Nepomnyachiy, Ryan Feehan, Nir Ben-Tal, Rachel Kolodny, Joanna S.G. Slusky
The paper traces the evolutionary pathway of outer membrane beta barrels, showing how repeat protein topology evolves through strand number changes without domain duplication, driven by membrane environment constraints.
bioRxiv · Apr 27, 2018 · PreprintBiophysics