Validation of a high-throughput screening assay for the characterization of cryoprotective agent toxicity
Justyna J. Jaskiewicz, Abby Callahan-Muller, Nora Gaby-Biegel, Zachary Glover, Rebecca D. Sandlin
The paper validates a high-throughput screening assay for CPA toxicity using T24 cells, showing a Z-factor of 0.75 and a 1.7% hit rate for 5 M CPA cocktails.
bioRxiv · May 26, 2025 · PreprintPharmacology & Toxicology