Design of highly potent anti-biofilm, antimicrobial peptides using explainable artificial intelligence
Karina Pikalyova, Tagir N. Akhmetshin, Alexey A. Orlov, Evan F. Haney, Noushin Akhoundsadegh, Jiaying You, Robert E. W. Hancock, Dragos Horvath, Gilles Marcou, Artem R Cherkasov, Alexandre A. Varnek
This study designs potent anti-biofilm antimicrobial peptides using an explainable AI framework, achieving high efficacy against MRSA biofilms.
Journal of Chemical Information and Modeling · Dec 23, 2025Peer-reviewedBioinformatics