The Cardiac Calcium Handling Machinery is Remodeled in Friedreich's Ataxia
R. Czornobil, O. A.- Assali, E. R.- Wood, D. R. Lynch, S. F. Noujaim, B. Chidipi
This study investigates cardiac dysfunction in Friedreich's Ataxia by analyzing calcium handling proteins and mitochondrial function in both mouse models and human samples, finding reduced expression of key proteins and mitochondrial abnormalities.
bioRxiv · Nov 9, 2023 · PreprintPhysiology