Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria
M. D. Kattke, J. E. Gosschalk, O. E. Martinez, G. Kumar, R. T. Gale, D. Cascio, M. R. Sawaya, M. Phillips, E. Brown, R. T. Clubb
This paper determines the structure of TagA, a glycosyltransferase involved in wall teichoic acid biosynthesis, and reveals its mechanism of catalysis and regulation by membrane interactions.
bioRxiv · Dec 28, 2018Biochemistry