Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing
C. M. Green, Z. Li, O. Novikova, V. R. Bacot-Davis, F. Gao, N. K. Banavali, H. Li, M. Belfort
The paper investigates the Prp8 intein in Cryptococcus neoformans, showing that copper and zinc inhibit intein splicing through distinct mechanisms, potentially affecting spliceosome function.
bioRxiv · Dec 20, 2018Biochemistry