Binding specificity of ASHH2 CW-domain towards H3K4me1 ligand is coupled to its structural stability through its α1-helix
M. S. Bril'kov, O. Dobrovolska, O. Oedegaard-Fougner, O. Stroemland, R. Aasland, O. Halskau
This study investigates how the structural stability of the ASHH2 CW-domain is coupled to its binding specificity for H3K4me1 through the α1-helix and loop regions.
bioRxiv · Aug 12, 2021Biophysics